Stimulatory Constituents of Eclipta Prostrata

نویسندگان

  • Mi Kyeong Lee
  • Na Ry Ha
  • Hyekyung Yang
  • Sang Hyun Sung
  • Choong Kim
چکیده

One flavonoid, diosmetin (1), and two isoflavonoids, 3′-hydroxybiochanin A (2) and 3′-O-methylorobol (3), were isolated from the methanol extract of Eclipta prostrata L. by a bioactivity-guided fractionation technique using primary cultures of mouse osteoblasts as an in vitro assay system. All three compounds significantly increased osteoblast differentiation as assessed by the alkaline phosphatase activity. Copyright © 2008 John Wiley & Sons, Ltd.

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تاریخ انتشار 2008